Every peptide gets a verdict. Here's what they mean.
Strong RCT evidence; widely prescribed or validated.
Meaningful human data accumulating; not yet RCT-strong.
Mechanism plausible; human trials sparse.
Not enough data to say anything responsible.
Active safety signals or misuse patterns.
Real assessments from our database — see the system in action.
Semaglutide works. The data is among the strongest of any peptide therapy approved in the last decade, and the cardiovascular signal in SELECT (2023) extends the case beyond glycemic and weight endpoints. It is not a casual or "longevity" peptide — it is a real medication with a real adverse event profile, and self-sourcing is genuinely dangerous given the dose-titration discipline required. Use it under clinical supervision with appropriate monitoring.
Read the full evidence →BPC-157 is a peptide that interesting researchers are paying attention to. It is also a peptide whose human evidence has not yet caught up to the popular narrative around it. There are reasonable people taking it under clinical supervision for specific orthopedic indications, and there are unreasonable people taking it for everything from a sore knee to a hangover; only the first group is acting in proportion to what we actually know. Worth tracking. Not yet worth recommending.
Read the full evidence →We rate Melanotan-II Cautionary, not because cosmetic tanning is morally wrong, but because the public discussion of this peptide systematically under-reports its real adverse event profile. Documented case reports include priapism requiring medical intervention, severe nausea and vomiting at typical doses, and — most concerningly — case reports of dysplastic and atypical nevi developing or worsening during use. The original commercial development pathway was abandoned and the molecule is sold today entirely through gray-market channels with no manufacturing oversight. If you are considering using it anyway, please do so with a dermatologist's mole map taken before you start.
Read the full evidence →Free to use. Built for people running their own protocols, and people deciding whether they should.
Read the verdicts. 20 monographs across 5 evidence states, growing weekly.
Open →Reconstitute a peptide accurately. Enter the vial, the bacteriostatic water, the target dose; get the units.
Open → Coming soonBuild a protocol you can hand to anyone. Doses, schedule, notes, reviewable history.
Open → Coming soonLog doses and timing. For people running their own protocols, and people supervising someone else's.
Open → Coming soonTrack outcomes over time. Subjective markers, lab results, protocol changes — your own data, kept private.
Open →